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Acetaminophen with Codeine


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Chemistry of Acetaminophen

The chemical formula of Acetaminophen is “N-(4-hydroxyphenyl) ethanamide, N-(4-hydroxyphenyl) acetamide”. The molecular weight of this drug has been calculated to be 151.163 g/mol and the purity of this substance in its purest forms has been calculated to be approximately equal to or greater than 99.9% while the total impurities in most cases in less than or equal to 0.1%.

The recommended storage temperature for the drugs is either room temperature or between 20oC to 25oC. In order to keep the drug preserved for a long period of time, it is advised to keep the drug at a low temperature of – 20oC while the stability of the molecule of this drug is known to be equal to or greater than two to three years. The chemical formulas of Acetaminophen is C8H9NO2.

Use of Acetaminophen

Before taking Acetaminophen with Codeine, it is wise to read the medication guide provided by your pharmacist. If you have to get a refill or have any questions, you should consult the pharmacist or doctor.

Patients should take acetaminophen with Codeine by mouth as directed by the medical practitioner. It can be taken with or without food. Taking it with food is especially high for patients with nausea.

If a patient is taking the drug in liquid form, he or she should use a drug-measuring tool to measure the prescribed dose carefully. They should avoid using a household spoon because they might take an incorrect dose. Those using the suspension should shake the bottle well before the treatment.

Dosage of Acetaminophen

A patient’s response to treatment and medical condition determines the Acetaminophen with Codeine dosage. The dose should not be increased, the medication time should not be increased, and the drug should not be taken more times than usual. The drug is more effective when used after the first signs of pain. The drug might not work well if the patient waits until the condition worsens.

Acetaminophen with Codeine can be used together with other long-acting opioid drugs. Ask your doctor the medicines that can be used safely along with this drug.

Effects of Acetaminophen

Users might experience withdrawal effects especially if they have taken this drug for a long time and in high doses. In such cases, they will suffer reactions like sweating, relentlessness, runny nose, watering eyes, nausea when they suddenly stop using this drug. To prevent these withdrawal reactions, the doctor might reduce the dosage gradually.  Also, talk to your doctor if this medication stops working well since the use of it for a long time might prevent it from working as well.

Patients risk addiction. The risk is higher if the patient has a substance use disorder like alcohol use. They should take this drug as prescribed to avoid this.

Warnings to put in mind

  • Overdose and misuse of this drug can lead to overdose and even death.
  • The drug can cause severe breathing problems, especially to first-timers. Notify your doctor if you start experiencing such.
  • The drug can be severe if taken by someone accidentally especially children.
  • The drug can cause liver damage due to acetaminophen
  • Because it is an opioid drug, the drug makes the user slow and drowsy that can cause dangerous effects that include accidents.
  • Avoid alcoholic products while under the medication of this drug
  • Using this drug while pregnant might cause withdrawal symptoms to the unborn baby. Talk to your doctor if you are planning to get pregnant or you are pregnant.
  • Do not administer this drug to children below 12 years.
  • Always talk to your doctor if you notice any abnormal effects after using this drug.


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